ncRNA basic information
ncRNA ID:
MIMAT0003247
ncRNA Database:
miRBase
ncRNA Name:
miR-582-5p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ATG7
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00877 (APRD00178, DB02439)
Drug Name:
Rapamycin
Drug Method:
Quantitative real-time polymerase chain reaction was used to detect mRNA level. Relative protein expression was detected by western blot. wound healing assay and transwell were used to determine migration and invasion of cells. in addtion, luciferase reporter assay and immunohistochemistry were performed.
Drug Response:
resistant
Cancer basic information
Cancer:
bladder cancer
Tissue/Cell:
tissue and cell line (SV-HUC-1, HT-1376, T24, J82, 5637, EJ )
Other information
Title:
Long noncoding RNA UCA1 targets miR-582-5p and contributes to the progression and drug resistance of bladder cancer cells through ATG7-mediated autophagy inhibition.
Journal:
Onco Targets Ther
Published:
2019
PubMed ID:
30666128