ncRNA basic information
ncRNA ID:
MI0000239
ncRNA Database:
miRBase
ncRNA Name:
miR-197
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NLK
ncRNA Pathway:
Wnt pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-197 and TUG1 in triple negative breast cancer cells was detected using qRT-PCR, cell viability assay , bioinformatic analysis , dual luciferase reporter assay , western blot and TOP flash/FOPflash assay ,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
tissue and cell line (MCF10 A,MCF7, T47D,MDA-MB-231 and BT549)
Other information
Title:
Long non-coding RNA TUG1 sponges miR-197 to enhance cisplatin sensitivity in triple negative breast cancer.
Journal:
Biomed Pharmacother
Published:
2018
PubMed ID:
30098551