ncRNA basic information
ncRNA ID:
MIMAT0000419
ncRNA Database:
miRBase
ncRNA Name:
miR-27b-3p
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
PPARGamma
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-27b-3p in the human anaplastic thyroid cancer cells was detected by CCK-8, real-time PCR, western blot analysis,dual-luciferase reporter assay,and ELISA.
Drug Response:
sensitive
Cancer basic information
Cancer:
anaplastic thyroid cancer
Tissue/Cell:
cell line (SW1736 and 8305C)
Other information
Title:
miR-27b-3p is Involved in Doxorubicin Resistance of Human Anaplastic Thyroid Cancer Cells via Targeting Peroxisome Proliferator-Activated Receptor Gamma.
Journal:
Basic Clin Pharmacol Toxicol
Published:
2018
PubMed ID:
29924913