ncRNA basic information
ncRNA ID:
MIMAT0000443
ncRNA Database:
miRBase
ncRNA Name:
miR-125a-5p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
STAT3
ncRNA Pathway:
STAT3 signaling pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-125a-5p was deteced by RT-qPCR, Western blot analysis, CCK-8 assay, Cell apoptosis assay, Would healing assay, Cell invasion assay, Plasmid construction and luciferase reporter assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
esophageal squamous cell carcinoma
Tissue/Cell:
tissue and cell line (ESCC )
Other information
Title:
MicroRNA-125a-5p enhances the sensitivity of esophageal squamous cell carcinoma cells to cisplatin by suppressing the activation of the STAT3 signaling pathway.
Journal:
Int J Oncol
Published:
2018
PubMed ID:
29767234