ncRNA basic information
ncRNA ID:
MIMAT0000087
ncRNA Database:
miRBase
ncRNA Name:
miR-30a-5p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
IGF1R
ncRNA Pathway:
AKT/P53 pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
After cisplatin (DDP) resistant melanoma cells (M8/DDP and SK-Mel-19/DDP) were established in-vitro, high-throughput screening of differentially expressed miRNAs between resistant cells and parental cells were performed.
Drug Response:
resistant
Cancer basic information
Cancer:
melanoma
Tissue/Cell:
cell line (M8, M8/DDP, SK-Mel-19, SK-Mel-19/DDP,HEK293T)
Other information
Title:
MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells.
Journal:
BMC Cancer
Published:
2018
PubMed ID:
29642855