ncRNA basic information
ncRNA ID:
MIMAT0004927
ncRNA Database:
miRBase
ncRNA Name:
miR-708-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-708-3p was deteced by RT-qPCR, Luciferase reporter assay, Western blot and immunohistochemistry assays, MTT assay and apoptotic cell detection, Invasion assay, and animal experiments.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-10A, MCF-7, MDA-MB-468 and MDA-MB-231)
Other information
Title:
MicroRNA-708-3p mediates metastasis and chemoresistance through inhibition of epithelial-to-mesenchymal transition in breast cancer.
Journal:
Cancer Sci
Published:
2018
PubMed ID:
29575368