ncRNA basic information
ncRNA ID:
MI0000447
ncRNA Database:
miRBase
ncRNA Name:
miR-128a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
BMI1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
Hep-2 and AMC-HN-8 cell lines were cultured. MiR-128a was upregulated utilizing lentiviral transfection. Through radiotherapy and chemotherapy assays, the function of miR-128a on chemoradiotherapy was evaluated. The correlation of miR-128a with BMI1 was identified by performing real-time PCR.
Drug Response:
sensitive
Cancer basic information
Cancer:
laryngeal cancer
Tissue/Cell:
cell line ( Hep-2,AMC-HN8)
Other information
Title:
Overexpressed miR-128a enhances chemoradiotherapy to laryngeal cancer cells and its correlation with BMI1.
Journal:
Future Oncol
Published:
2018
PubMed ID:
29186980