ncRNA basic information
ncRNA ID: MI0000783
ncRNA Database: miRBase
ncRNA Name: miR-375
ncRNA Type: miRNA
ncRNA Expression: down-regulated
ncRNA Method: RT-PCR
ncRNA Target Gene: NA
ncRNA Pathway: NA
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB00997 (APRD00185, DB05331, DB05847)
Drug Name: Doxorubicin
Drug Method: Serum samples were obtained from 95 patients with osteosarcoma and 95 healthy individuals. miR-375 expression was detected by real-time polymerase chain reaction. The associations of serum miR-375 expression with the patients¡¯ clinicopathological characteristics and prognosis were then evaluated. Receiver operating characteristic curve analysis was performed to obtain the potential value of serum miR-375 as a biomarker for osteosarcoma diagnosis and chemosensitivity prediction.
Drug Response: resistant
Cancer basic information
Cancer: osteosarcoma
Tissue/Cell: tissue
Other information
Title: MicroRNA-375 as a potential serum biomarker for the diagnosis, prognosis, and chemosensitivity prediction of osteosarcoma.
Journal: J Int Med Res
Published: 2018
PubMed ID: 29115164