ncRNA basic information
ncRNA ID:
MI0000650
ncRNA Database:
miRBase
ncRNA Name:
miR-200c
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
methylation-specific PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00002 (BTD00071, BIOD00071)
Drug Name:
Cetuximab
Drug Method:
The expression levels of miRNA were determined by methylation-specific PCR and those of protein were by Western blot analysis. Cell migration was detected by invasion assay,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung non-small cell carcinoma
Tissue/Cell:
cell line (Calu-1, NCI H520, SKMES-1,H596,Calu-3, NCI-H522,NCI-H1395,NCI-H1299, NCI-H460 )
Other information
Title:
Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer.
Journal:
Mol Cancer Res
Published:
2010
PubMed ID:
20696752