ncRNA basic information
ncRNA ID:
MI0000070/MI0000115
ncRNA Database:
miRBase
ncRNA Name:
miR-16
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
BCL2
ncRNA Pathway:
the mitochondrial pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-96 in human cancer cells was detected using quantitative RT-PCR,luciferase activity assay, western blot analysis,and apoptosis assay,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
cell line (SGC7901,SGC7901/VCR)
Other information
Title:
miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells.
Journal:
Int J Cancer
Published:
2008
PubMed ID:
18449891