ncRNA basic information
ncRNA ID:
MI0000083
ncRNA Database:
miRBase
ncRNA Name:
miR-26a
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
GSK3Beta
ncRNA Pathway:
miR-26a-GSK3Beta-Mcl1 pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of AC023115.3 and miR-26a in malignant glioma cells was detected using western blot, microarray and computational analysis, dual-luciferase reporter assay, MTT assay, RIP assay,Real-time RT-PCR and RT-PCR, fluorescence microscopy and transmission electron microscopy,etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
glioblastoma
Tissue/Cell:
cell line (U87MG, U251MG)
Other information
Title:
Long non-coding RNA AC023115.3 suppresses chemoresistance of glioblastoma by reducing autophagy.
Journal:
Biochim Biophys Acta Mol Cell Res
Published:
2017
PubMed ID:
28499919