ncRNA basic information
ncRNA ID:
MIMAT0004692
ncRNA Database:
miRBase
ncRNA Name:
miR-340-5p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
LPAATBeta
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
osteosarcoma
Tissue/Cell:
cell line ( MG-63, Saos-2,MG-63/CDDP,Saos-2/CDDP)
Other information
Title:
MicroRNA-340-5p modulates cisplatin resistance by targeting LPAATBeta in osteosarcoma.
Journal:
Braz J Med Biol Res
Published:
2017
PubMed ID:
28443990