ncRNA basic information
ncRNA ID:
MI0001641
ncRNA Database:
miRBase
ncRNA Name:
miR-429
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ZEB1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
Using miRNA profiles of a panel of cisplatin-resistant (SKOV3/DDP) cells, we validated data using quantitative real time-PCR (QRT-PCR), and studied the effects of miR-429 on cancer cell chemo-sensitivity, using gain- and loss-of-function studies.
Drug Response:
sensitive
Cancer basic information
Cancer:
epithelial ovarian cancer
Tissue/Cell:
cell line ( SKOV3,SKOV3/DDP)
Other information
Title:
Downregulation of miR-429 contributes to the development of drug resistance in epithelial ovarian cancer by targeting ZEB1.
Journal:
Am J Transl Res
Published:
2017
PubMed ID:
28386361