ncRNA basic information
ncRNA ID:
MI0000438
ncRNA Database:
miRBase
ncRNA Name:
miR-15b
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
TRIM14
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined byReal-time PCR and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
oral tongue squamous cell cancer
Tissue/Cell:
cell line ( SCC25,SCC25-res)
Other information
Title:
miR-15b inhibits cancer-initiating cell phenotypes and chemoresistance of cisplatin by targeting TRIM14 in oral tongue squamous cell cancer.
Journal:
Oncol Rep
Published:
2017
PubMed ID:
28350138