ncRNA basic information
ncRNA ID:
MI0003135
ncRNA Database:
miRBase
ncRNA Name:
miR-495
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
TSPAN12
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of TSPAN12 and miR-495 in small cell lung cancer cells was detected using quantitative RT-PCR, western blot, CCK-8 assays, cell migration assay, tumor xenograft experiment and dual luciferase reporter assay, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung small cell carcinoma
Tissue/Cell:
cell line (NCI-H69, NCI-H446,NCI-H69AR)
Other information
Title:
TSPAN12 promotes chemoresistance and proliferation of SCLC under the regulation of miR-495.
Journal:
Biochem Biophys Res Commun
Published:
2017
PubMed ID:
28302484