ncRNA basic information
ncRNA ID:
MI0000466/MI0000467/MI0000468
ncRNA Database:
miRBase
ncRNA Name:
miR-9
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
ABCB1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Adriamycin
Drug Method:
The expression levels of miRNA were determined by Real-time PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs. etc
Drug Response:
sensitive
Cancer basic information
Cancer:
chronic myeloid leukemia
Tissue/Cell:
cell line ( K562,K562/ADR)
Other information
Title:
miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1.
Journal:
Oncol Rep
Published:
2017
PubMed ID:
28260112