ncRNA basic information
ncRNA ID:
MI0000253
ncRNA Database:
miRBase
ncRNA Name:
miR-148a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
Rab14
ncRNA Pathway:
the caspase-dependent pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined byreverse transcriptase-polymerase chain reaction (RT-PCR) and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
kidney cancer
Tissue/Cell:
cell line
Other information
Title:
miR-148a increases the sensitivity to cisplatin by targeting Rab14 in renal cancer cells.
Journal:
Int J Oncol
Published:
2017
PubMed ID:
28098870