ncRNA basic information
ncRNA ID:
MI0000462
ncRNA Database:
miRBase
ncRNA Name:
miR-152
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ALCAM
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00675 (APRD00123)
Drug Name:
Tamoxifen
Drug Method:
The role of miR-148a and miR-152 in ERt breast cancer cells was detected by qRT-PCR, western blot analysis,dual luciferase assay, and follow cytometric analysis.etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
tissue and cell line ( MCF-7 )
Other information
Title:
MiR-148a and miR-152 reduce tamoxifen resistance in ER+ breast cancer via downregulating ALCAM.
Journal:
Biochem Biophys Res Commun
Published:
2017
PubMed ID:
28063929