ncRNA basic information
ncRNA ID:
MI0000080/MI0000081
ncRNA Database:
miRBase
ncRNA Name:
miR-24
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
FIH1
ncRNA Pathway:
FIH1/HIFalpha pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Reverse transcription- polymerase chain reaction (RT-PCR) and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.
Drug Response:
resistant
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (T47D, BT-549, MDA-MB-231, and MCF-7)
Other information
Title:
MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer.
Journal:
Oncotarget
Published:
2017
PubMed ID:
28061479