ncRNA basic information
ncRNA ID:
MI0003134
ncRNA Database:
miRBase
ncRNA Name:
miR-494
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01204 (APRD00371)
Drug Name:
Mitoxantrone
Drug Method:
The role of miR-494 in acute myeloid leukemia cells was detected by real-time PCR, microRNA array analysis.western blot analysis,MTT assay,apoptosis analysis,subcutaneous tumor formation assay,and Xenograft mouse model.etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
acute myeloid leukemia
Tissue/Cell:
tissue and cell line
Other information
Title:
MicroRNA-494 Activation Suppresses Bone Marrow Stromal Cell-Mediated Drug Resistance in Acute Myeloid Leukemia Cells.
Journal:
J Cell Physiol
Published:
2017
PubMed ID:
27696394