ncRNA basic information
ncRNA ID:
MI0005567
ncRNA Database:
miRBase
ncRNA Name:
miR-760
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
Nanog
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
Real-time PCR was performed to measure the mRNA expression of miR-760 and Nanog. Western blot was used to determine the protein expression of Nanog and mesenchymal and epithelial markers. Cell viability was measured by the CCK-8 assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line ( Bcap37, MCF-7, MDA-MB-231)
Other information
Title:
miR-760 mediates chemoresistance through inhibition of epithelial mesenchymal transition in breast cancer cells.
Journal:
Eur Rev Med Pharmacol Sci
Published:
2016
PubMed ID:
27981531