ncRNA basic information
ncRNA ID:
MI0003607
ncRNA Database:
miRBase
ncRNA Name:
miR-595
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ABCB1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Quantitative real-time PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. he CCK-8 assay was used to monitor the growth of the cells.
Drug Response:
sensitive
Cancer basic information
Cancer:
ovarian cancer
Tissue/Cell:
cell line (HG-SOC, HO8910, SKOV-3, HO8910PM, ES2,FTE187)
Other information
Title:
MicroRNA-595 sensitizes ovarian cancer cells to cisplatin by targeting ABCB1.
Journal:
Oncotarget
Published:
2016
PubMed ID:
27893429