ncRNA basic information
ncRNA ID:
MI0000469
ncRNA Database:
miRBase
ncRNA Name:
miR-125a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00541 (APRD00495)
Drug Name:
Vincristine
Drug Method:
The expression levels of miRNA were determined byReal-time PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
laryngeal cancer
Tissue/Cell:
cell line (Hep-2)
Other information
Title:
Inhibition of HAX-1 by miR-125a reverses cisplatin resistance in laryngeal cancer stem cells.
Journal:
Oncotarget
Published:
2016
PubMed ID:
27880721