ncRNA basic information
ncRNA ID:
MI0000299
ncRNA Database:
miRBase
ncRNA Name:
miR-222
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
PTEN/Akt/p27kip1 pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Adriamycin
Drug Method:
The role of miR-222 in human breast cancer cells was detected by qRT-PCR, MTT assay,flow cytometry.western blot,and Immunofluorescence microscope.etc.
Drug Response:
resistant
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7/Adr,MCF-7/S)
Other information
Title:
miR-222 induces Adriamycin resistance in breast cancer through PTEN/Akt/p27kip1 pathway.
Journal:
Tumour Biol
Published:
2016
PubMed ID:
27699665