ncRNA basic information
ncRNA ID:
MI0000650
ncRNA Database:
miRBase
ncRNA Name:
miR-200c
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
ZEB1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB08865 (DB08700)
Drug Name:
Crizotinib
Drug Method:
The role of miR-200c in human lung cancer cells was detected by RT?qPCR, cell viability and invasion assays,and lLuciferase reporter assay.etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung cancer
Tissue/Cell:
cell line (NCI-2228, A549, H460)
Other information
Title:
miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1.
Journal:
Mol Med Rep
Published:
2016
PubMed ID:
27666124