ncRNA basic information
ncRNA ID:
MI0000285
ncRNA Database:
miRBase
ncRNA Name:
miR-205
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
VEGFA and FGF2
ncRNA Pathway:
PI3K/AKT signaling pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-205 was detected by MTT assay, Drug resistance clonogenic assay, Gene expression analysis, Annexin V staining, Caspase activity, Enzyme-linked immunosorbent assay (ELISA), etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7,MCF-7/A02,K562, HL60, BJAB)
Other information
Title:
miRNA-205 targets VEGFA and FGF2 and regulates resistance to chemotherapeutics in breast cancer.
Journal:
Cell Death Dis
Published:
2016
PubMed ID:
27362808