ncRNA basic information
ncRNA ID:
MI0000274
ncRNA Database:
miRBase
ncRNA Name:
miR-187
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
In this study, we performed global miRNA profiling of EAC patient tumors to identify miRNAs that may be involved in tumor resistance to neoadjuvant CRT. We identified miR-187 as a potential novel biomarker of treatment response and a potential therapeutic target that could enhance patient sensitivity to radiotherapy and chemotherapy.
Drug Response:
sensitive
Cancer basic information
Cancer:
esophageal adenocarcinoma
Tissue/Cell:
cell line (OE33 P, OE33 R ,OE33, SK-GT-4)
Other information
Title:
Low miR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma.
Journal:
Mol Med
Published:
2016
PubMed ID:
27254108