ncRNA basic information
ncRNA ID:
MIMAT0004679
ncRNA Database:
miRBase
ncRNA Name:
miRNA-296-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
CX3CR1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by quantitative real-time-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. The CCK-8 assay was used to monitor the growth of the cells.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung cancer
Tissue/Cell:
cell line (A549, H157, NIH-H358, Calu-3, LAX, HCC827, LTEP-2, D6, SPCA1,BEAS-2B)
Other information
Title:
miRNA-296-3p modulates chemosensitivity of lung cancer cells by targeting CX3CR1.
Journal:
Am J Transl Res
Published:
2016
PubMed ID:
27186308