ncRNA basic information
ncRNA ID:
MI0006431
ncRNA Database:
miRBase
ncRNA Name:
miR-1284
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
EIF4A1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00541 (APRD00495)
Drug Name:
Vincristine
Drug Method:
The expression levels of miRNA were determined by quantitative reverse transcription real-time polymerase chain reaction and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. Cell migration was detected by invasion assay. A wound healing assay was performed to examine the capacity of cell migration.
Drug Response:
sensitive
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
tissue and cell line (SGC7901/VCR )
Other information
Title:
MiR-1284 modulates multidrug resistance of gastric cancer cells by targeting EIF4A1.
Journal:
Oncol Rep
Published:
2016
PubMed ID:
26936591