ncRNA basic information
ncRNA ID:
MI0000457
ncRNA Database:
miRBase
ncRNA Name:
miR-141
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-141 was detected by quantitative real-time PCR, MTT assay, cell cycle assay, Wound healing assay, Cisplatin sensitivity assay, In vivo tumor growth assay, luciferase reporter assay, and FUS downregulation assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
neuroblastoma
Tissue/Cell:
cell line (IMR-32, SH-SY5Y, S-K-NAS,NB-1691, LAN-5, LAN-6)
Other information
Title:
MicroRNA-141 and its associated gene FUS modulate proliferation, migration and cisplatin chemosensitivity in neuroblastoma cell lines.
Journal:
Oncol Rep
Published:
2016
PubMed ID:
26936280