ncRNA basic information
ncRNA ID:
MI0000488/MI0000732
ncRNA Database:
miRBase
ncRNA Name:
miR-194
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
FOXA1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by quantitative real-time PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. The CCK-8 assay was used to monitor the growth of the cells. Cell migration was detected by transwell migration and invasion assay.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung non-small cell carcinoma
Tissue/Cell:
tissue and cell line (A549, SPC-A1, 95C, 95D, NCI-H1299, SK-MES-1,16HBE)
Other information
Title:
miR-194 inhibits the proliferation, invasion, migration, and enhances the chemosensitivity of non-small cell lung cancer cells by targeting forkhead box A1 protein.
Journal:
Oncotarget
Published:
2016
PubMed ID:
26909612