ncRNA basic information
ncRNA ID:
NA
ncRNA Database:
miRBase
ncRNA Name:
miR-200
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ZEB1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB09079
Drug Name:
Nintedanib
Drug Method:
The role of miR-125a was detected by MTT assay, Hoechst staining assay, RNA extraction and RT-PCR assay, Western blot, dual luciferase activityassay and animal experiment.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung non-small cell carcinoma
Tissue/Cell:
cell line (A549, PC-3, PC-9, PC-14, NCI-HCC827, NCI-H1650, NCI-H1975, LC-2/ad, RERF-LC-KJ adeno-carcinoma (AC),PC-1, PC-10, LK-2, SQ5, QG56, EBC-1,SQ)
Other information
Title:
miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.
Journal:
Int J Oncol
Published:
2016
PubMed ID:
26783187