ncRNA basic information
ncRNA ID:
MI0000088
ncRNA Database:
miRBase
ncRNA Name:
miR-30a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by quantitative real-time polymerase chain reaction (qPCR) and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.TUNEL staining was used to detect apoptotic cell death. Xenografts in nude mice was used to test the role of miR-30a .
Drug Response:
sensitive
Cancer basic information
Cancer:
ovarian carcinoma
Tissue/Cell:
cell line (A2780,A2780 CIS, A2780 TAX,2008C13 (CIS),SKOV-3 )
Other information
Title:
miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma.
Journal:
Oncotarget
Published:
2016
PubMed ID:
26675258