ncRNA basic information
ncRNA ID: NA
ncRNA Database: miRBase
ncRNA Name: miR-106~25
ncRNA Type: miRNA
ncRNA Expression: up-regulated
ncRNA Method: NA
ncRNA Target Gene: EP300
ncRNA Pathway: miR-106b~25 cluster/EP300/E-cadherin pathway
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB01229 (APRD00259, DB05261, DB05927, DB05526, DB05281)
Drug Name: Paclitaxel
Drug Method: The role of miR-106b~25 cluster in breast cancer cells was detected using drug resistance clonogenic assay, drug efflux assay, P-glycoprotein expression assay, Gene expression analysis, caspase-9 and -3/-7 using Caspase-Glo assays, etc.
Drug Response: resistant
Cancer basic information
Cancer: breast cancer
Tissue/Cell: cell line
Other information
Title: MiR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300.
Journal: Oncol Rep
Published: 2016
PubMed ID: 26573761