ncRNA basic information
ncRNA ID:
MI0000263/MI0000264/ MI0000265
ncRNA Database:
miRBase
ncRNA Name:
miR-7
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
SMARCD1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-7 in lung cancer cells was detected using WST-1 cell viability assay, luciferase assays, Annexin-V FITC apoptosis assay, Real Time quantitative PCR and microRNA targeting prediction, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung cancer
Tissue/Cell:
cell line (A549, H1299, H1975, HCC827,HEK293T )
Other information
Title:
MicroRNA-7 Compromises p53 Protein-dependent Apoptosis by Controlling the Expression of the Chromatin Remodeling Factor SMARCD1.
Journal:
J Biol Chem
Published:
2016
PubMed ID:
26542803