ncRNA basic information
ncRNA ID:
MI0000460
ncRNA Database:
miRBase
ncRNA Name:
miR-144
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
Beclin-1
ncRNA Pathway:
autophagy pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Quantitative real-time PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. The CCK-8 assay was used to monitor the growth of the cells .
Drug Response:
resistant
Cancer basic information
Cancer:
prostate cancer
Tissue/Cell:
cell line ( PC3, LNCap)
Other information
Title:
VEGF-activated miR-144 regulates autophagic survival of prostate cancer cells against Cisplatin.
Journal:
Tumour Biol
Published:
2015
PubMed ID:
26566625