ncRNA basic information
ncRNA ID:
NA
ncRNA Database:
miRBase
ncRNA Name:
miR-200
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00531 (APRD00408)
Drug Name:
Cyclophosphamide
Drug Method:
The expression levels of miRNA were determined by quantitative RT-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. Cell migration was detected by migration and invasion assay. Flow Cytometric Assay was used to determine if cells were viable, apoptotic, or necrotic.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
tissue and cell line (Tri-PyMT)
Other information
Title:
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.
Journal:
Nature
Published:
2015
PubMed ID:
26560033