ncRNA basic information
ncRNA ID:
MI0000650
ncRNA Database:
miRBase
ncRNA Name:
miR-200c
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00958 (APRD00466)
Drug Name:
Carboplatin
Drug Method:
The expression levels of miRNA were determined by Real-time quantitative PCR (qPCR) and those of protein were by Western blot analysis. Flow Cytometric Assay was used to determine if cells were viable, apoptotic, or necrotic.
Drug Response:
resistant
Cancer basic information
Cancer:
ovarian carcinoma
Tissue/Cell:
cell line (OVCAR-3,MES-OV,OVCAR-3/TP, MES-OV/TP)
Other information
Title:
The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells.
Journal:
Mol Oncol
Published:
2015
PubMed ID:
26025631