ncRNA basic information
ncRNA ID:
MI0000737
ncRNA Database:
miRBase
ncRNA Name:
miR-200a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01229 (APRD00259, DB05261, DB05927, DB05526, DB05281)
Drug Name:
Paclitaxel
Drug Method:
The expression levels of miRNA were determined by qRT-PCR . MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.The CCK-8 assay was used to monitor the growth of the cells . In vivo xenograft experiments was used to test the tole of miR-200a .
Drug Response:
sensitive
Cancer basic information
Cancer:
ovarian cancer
Tissue/Cell:
cell line (OVCAR-3)
Other information
Title:
Upregulation of microRNA-200a associates with tumor proliferation, CSCs phenotype and chemosensitivity in ovarian cancer.
Journal:
Neoplasma
Published:
2015
PubMed ID:
25997962