ncRNA basic information
ncRNA ID:
MIMAT0000418
ncRNA Database:
miRBase
ncRNA Name:
miR-23b-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
ATG12 and HMGB2
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00541 (APRD00495)
Drug Name:
Vincristine
Drug Method:
The expression levels of miRNA were determined by quantitative real-time PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
stomach cancer
Tissue/Cell:
cell line (SGC7901,SGC7901/VCR)
Other information
Title:
miR-23b-3p regulates the chemoresistance of gastric cancer cells by targeting ATG12 and HMGB2.
Journal:
Cell Death Dis
Published:
2015
PubMed ID:
25996293