ncRNA basic information
ncRNA ID:
MI0000284
ncRNA Database:
miRBase
ncRNA Name:
miR-204
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
RT-qPCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
predicted
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
ndividual subcultures of chemosensitive SH-SY5Y and UKF-NB-3 cells were rendered chemoresistant to doxorubicin (SH-SY5Y, UKF-NB-3) or etoposide (SH-SY5Y). In each validated chemoresistance model, the parental and subcultured cell lines were analysed for miRNA expression profiling, using a high-throughput quantitative polymerase chain reaction (RT-qPCR) miRNA profiling platform for a total of 668 miRNAs.
Drug Response:
resistant
Cancer basic information
Cancer:
neuroblastoma
Tissue/Cell:
cell line (SH-SY5Y, UKF-NB-3)
Other information
Title:
Identification of miRNAs contributing to neuroblastoma chemoresistance.
Journal:
Comput Struct Biotechnol J
Published:
2015
PubMed ID:
25973145