ncRNA basic information
ncRNA ID:
MI0000294/MI0000295
ncRNA Database:
miRBase
ncRNA Name:
miR-218
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
The role of miR-218 in breast cancer cells was detected using MTT assay, drug resistance clonogenic assay, gene expression analysis, western blot, annexin V staining and caspase activity, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7, Cal51, MCF-7/ADR,CALDOX)
Other information
Title:
miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer.
Journal:
Breast Cancer Res Treat
Published:
2015
PubMed ID:
25900794