ncRNA basic information
ncRNA ID:
MI0000085
ncRNA Database:
miRBase
ncRNA Name:
miR-27a
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
Northern blot,qRT-PCR
ncRNA Target Gene:
MDR1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00541 (APRD00495)
Drug Name:
Vincristine
Drug Method:
Here we have firstly investigated the roles of miR-27a in multidrug resistance of esophageal squamous cell carcinoma using MTT assay, flow cytometry assay, and reporter gene assay, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
esophageal squamous cell carcinoma
Tissue/Cell:
cell line (ECA109, TE-13)
Other information
Title:
Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma.
Journal:
Dig Dis Sci
Published:
2010
PubMed ID:
19960259