ncRNA basic information
ncRNA ID:
MI0000079
ncRNA Database:
miRBase
ncRNA Name:
miR-23a
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
real-time qRT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
JNK signaling pathway
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Real-time quantitative reverse transcription PCR and those of protein were by Western blot analysis. Cell apoptosis was analyzed with an Annexin V-EGFP apoptosis detection kit coupled with flow cytometric analysis .
Drug Response:
resistant
Cancer basic information
Cancer:
tongue squamous cell carcinoma
Tissue/Cell:
cell line (SCC-4, Tca8113)
Other information
Title:
miR-23a promotes cisplatin chemoresistance and protects against cisplatin-induced apoptosis in tongue squamous cell carcinoma cells through Twist.
Journal:
Oncol Rep
Published:
2015
PubMed ID:
25501015