ncRNA basic information
ncRNA ID:
MI0000475
ncRNA Database:
miRBase
ncRNA Name:
miR-136
ncRNA Type:
miRNA
ncRNA Expression:
down-regulated
ncRNA Method:
qRT-PCR,RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by quantitative real-time PCR .Cell migration was detected by transwell migration and invasion assay. Flow Cytometric Assay was used to determine if cells were viable, apoptotic, or necrotic.A wound healing assay was performed to examine the capacity of cell migration.
Drug Response:
resistant
Cancer basic information
Cancer:
epithelial ovarian cancer
Tissue/Cell:
cell line (EOC, OV2008, C13)
Other information
Title:
Expression of miR-136 is associated with the primary cisplatin resistance of human epithelial ovarian cancer.
Journal:
Oncol Rep
Published:
2015
PubMed ID:
25482209