ncRNA basic information
ncRNA ID:
MIMAT0000459
ncRNA Database:
miRBase
ncRNA Name:
miR-193a-3p
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
HOXC9,SRSF2,PLAU,HIC2
ncRNA Pathway:
DNA damage response/oxidative stress pathway axis
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB01229 (APRD00259, DB05261, DB05927, DB05526, DB05281)
Drug Name:
Paclitaxel
Drug Method:
The expression levels of miRNA were determined by qRT-PCR and those of protein were by Western blot analysis. Luciferase activity assay was used to verify the target genes of miRNAs. Animal experiments was used to test the role of miR-193a-3p .
Drug Response:
resistant
Cancer basic information
Cancer:
bladder cancer
Tissue/Cell:
cell line ( 5637, H-bc)
Other information
Title:
MiR-193a-3p promotes the multi-chemoresistance of bladder cancer by targeting the HOXC9 gene.
Journal:
Cancer Lett
Published:
2015
PubMed ID:
25444900