ncRNA basic information
ncRNA ID:
MI0000294/MI0000295
ncRNA Database:
miRBase
ncRNA Name:
miR-218
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
BRCA1
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The role of miR-218 in breast cancer cells was detected using quantitative real-time PCR, cell viability, apoptosis assays, and colony growth assay, luciferase assay, comet assay and western blot analysis, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7,HEK-293, MCF-7/DDP)
Other information
Title:
MiR-218 regulates cisplatin chemosensitivity in breast cancer by targeting BRCA1.
Journal:
Tumour Biol
Published:
2015
PubMed ID:
25394901