ncRNA basic information
ncRNA ID:
MI0000489
ncRNA Database:
miRBase
ncRNA Name:
miR-195
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
qRT-PCR
ncRNA Target Gene:
BCL2L2
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00997 (APRD00185, DB05331, DB05847)
Drug Name:
Doxorubicin
Drug Method:
In this study, we utilized microRNA array and real-time PCR to identify that some microRNAs different expression level in cell lines. In vitro cell viability assay showed that the role of miR-195 in colon cancer cells .
Drug Response:
sensitive
Cancer basic information
Cancer:
colon cancer
Tissue/Cell:
cell line ( HT29, LOVO,HT29/DOX, LOVO/DOX )
Other information
Title:
MicroRNA-195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA.
Journal:
J Cell Physiol
Published:
2015
PubMed ID:
23526568