ncRNA basic information
ncRNA ID:
MI0000263/MI0000264/ MI0000265
ncRNA Database:
miRBase
ncRNA Name:
miR-7
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
RT-PCR
ncRNA Target Gene:
NA
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00072 (BTD00098, BIOD00098)
Drug Name:
Trastuzumab
Drug Method:
The role of miR-7 in breast cancer cells was detected using micro RNA expression profiling, western blot, colony formation assay, cell cycle and cell migration analysis, etc.
Drug Response:
sensitive
Cancer basic information
Cancer:
breast cancer
Tissue/Cell:
cell line (MCF-7)
Other information
Title:
MicroRNA-7 inhibits multiple oncogenic pathways to suppress HER2Delta16 mediated breast tumorigenesis and reverse trastuzumab resistance.
Journal:
PLoS One
Published:
2014
PubMed ID:
25532106