ncRNA basic information
ncRNA ID: MI0000114
ncRNA Database: miRBase
ncRNA Name: miR-107
ncRNA Type: miRNA
ncRNA Expression: up-regulated
ncRNA Method: real-time qRT-PCR
ncRNA Target Gene: CDK8
ncRNA Pathway: NA
Evidence (ncRNA-drug): validated
drug basic information
Drug ID: DB00515 (APRD00359)
Drug Name: Cisplatin
Drug Method: The expression levels of miRNA were determined by Real-time quantitative reverse transcription-PCR and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response: sensitive
Cancer basic information
Cancer: lung non-small cell carcinoma
Tissue/Cell: cell line (A549)
Other information
Title: miR-107 regulates cisplatin chemosensitivity of A549 non small cell lung cancer cell line by targeting cyclin dependent kinase 8.
Journal: Int J Clin Exp Pathol
Published: 2014
PubMed ID: 25400821