ncRNA basic information
ncRNA ID:
MI0000114
ncRNA Database:
miRBase
ncRNA Name:
miR-107
ncRNA Type:
miRNA
ncRNA Expression:
up-regulated
ncRNA Method:
real-time qRT-PCR
ncRNA Target Gene:
CDK8
ncRNA Pathway:
NA
Evidence (ncRNA-drug):
validated
drug basic information
Drug ID:
DB00515 (APRD00359)
Drug Name:
Cisplatin
Drug Method:
The expression levels of miRNA were determined by Real-time quantitative reverse transcription-PCR and those of protein were by Western blot analysis. MTT assay was used to test the drug-resistant phenotype changes in cancer cells via overregulation of miRNAs.
Drug Response:
sensitive
Cancer basic information
Cancer:
lung non-small cell carcinoma
Tissue/Cell:
cell line (A549)
Other information
Title:
miR-107 regulates cisplatin chemosensitivity of A549 non small cell lung cancer cell line by targeting cyclin dependent kinase 8.
Journal:
Int J Clin Exp Pathol
Published:
2014
PubMed ID:
25400821